Preparation of phenyloxadiazolylanilines

Details Preparation of phenyloxadiazolylanilines Preparation of phenyloxadiazolylanilines

1990-02-01

1992-04-14

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D27106

Patent

active

051049910

ABSTRACT:
Phenyloxadiazolylanilines are prepared by reaction of a benzonitrile in an aqueous reaction medium first with hydroxylamine or an acid addition salt thereof to give a benzamideoxime and then with an isatoic anhydride to give a non-cyclic compound and subsequent cyclization, the reaction sequence being carried out in the presence of an anionic surfactant.

REFERENCES:
Chemical Pharmaceutical Bulletin, Band 23, Nr. 12, Dec. 1974, Seiten 3178-3183, Tokyo, JP: K. Nagahara et al.: "Sur la formation d'Oxadiazoles-1,2,4 par action de benzamidoximes sur des anhydrides isatoiques" *Insgesam t* .
Ullmanns Encyklopadie Der Technischen Chemie, 4th edition, vol 22, pp. 468-488.
Schwartz Surface Active Agents vol. I, p. 513 (1949).

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