Thiazole derivatives

Details Thiazole derivatives Thiazole derivatives

1990-05-29

1992-04-14

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546209, 548184, 548186, 548191, 548193, 548194, 548203, C07D27742, A61K 31425

Patent

active

051048892

ABSTRACT:
This invention provides thiazole derivative of the general formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and A are as defined above, and salts thereof. These compounds have particularly potent angiogenesis inhibiting activity.

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patent: 3467666 (1969-09-01), Dexter
patent: 4451471 (1984-05-01), Ferrini et al.
patent: 4457936 (1984-07-01), Draeger et al.
patent: 4636516 (1987-01-01), Kubo et al.
Deshpande, R. N. et al., "Aryl 5-Nitro-2-thiazolyl Sulphides, Sulphones and Ethers as Potential Antibacterials", Journal f. prakt. Chemie, vol. 316, No. 2 (1974), pp. 349-352.

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