Particle counting nucleic acid hybridization assays

Details Particle counting nucleic acid hybridization assays Particle counting nucleic acid hybridization assays

1988-02-09

1992-04-14

Wax, Robert A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

436501, 536 26, 536 27, 935 77, 935 78, C12Q 168, G01N 33566, C07H 1512, C12N 1500

Patent

active

051047918

ABSTRACT:
An improved nucleic acid hybridization assay, relying on particle counting, is provided. Presence and quantity of target nucleic acid is determined by detecting, upon hybridization, signals associated with particle aggregation or coincident signals from particles and reporters.

REFERENCES:
patent: 4806463 (1989-03-01), Goodchild et al.
Walker et al., The Language of Biotechnology, pp. 21-22 and 35-36, American Chemical Society, 1988.

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