4-Hydroxy-5-substituted-3-(2H)-isothiazolone-1,1-dioxide derivat

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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548206, 548213, C07D27502, A61K 3144

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active

044289561

ABSTRACT:
4-Hydroxy-5-substituted-3(2H)-isothiazolone-1,1-dioxide derivatives of the formula: ##STR1## where X and Y are independently selected from the group consisting of hydrogen, halogen, and C.sub.1-6 alkyl; provided that positions 2 and 6 of the substituted phenyl moiety may not be substituted; and n is 0 or 1;

REFERENCES:
patent: 3849430 (1974-11-01), Lewis
patent: 4067878 (1978-01-01), Miller
patent: 4346094 (1982-08-01), Beck et al.
Lewis et al., J. Het. Chem., 8, p. 591 (1971).
Burger, Medicinal Chemistry, p. 42.
Randall et al., J. Med. Chem., 22, p. 608.

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