Process for the biotechnological preparation of l-thienylalanine

Details Process for the biotechnological preparation of l-thienylalanine Process for the biotechnological preparation of l-thienylalanine

1993-07-29

1996-01-02

Knode, Marian C.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

435193, 435849, C12P 1304, C12N 910

Patent

active

054807867

ABSTRACT:
L-Thienylalanines are prepared via the hydantoin or the azlactone route. The starting substances used for the biotransformation are 2-hydroxy-3-thienylacrylic acids. The innovative step consists in the transamination of the enol form of the 2-hydroxy-3-thienylacrylic acids to give L-thienylalanines with the aid of biotransformation. The transaminiation is carried out in the presence of L-aspartic acid or L-glutamic acid as amino donor.

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