Process for preparing 2(1H)-quinazolinone derivatives

Details Process for preparing 2(1H)-quinazolinone derivatives Process for preparing 2(1H)-quinazolinone derivatives

1976-12-06

1983-06-07

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

544119, 544251, 544284, 544286, C07D41304, C07D41306, C07D40104, C07D40504

Patent

active

043872239

ABSTRACT:
2(1H)-Quinazolinone and quinazolinethione derivatives having excellent pharmacological activities are produced in high yield with high purity by heating the corresponding 3,4-dihydro-2(1H)-quinazolinone or quinazolinethione derivatives together with sulfur in an inert solvent.

REFERENCES:
patent: 3509149 (1970-04-01), Cusic et al.
patent: 3560501 (1971-02-01), Walker
patent: 3686174 (1972-08-01), Cooke et al.
patent: 3748331 (1973-07-01), Cooke et al.
patent: 3937705 (1976-02-01), Hardtmann
patent: 4048168 (1977-09-01), Yamamoto et al.
patent: 4202974 (1980-05-01), Yamamoto et al.
Ritter, "J. Amer. Chem.Soc.", vol. 55, 1933, pp. 3322-3325.
Merck Index, Ninth Edition, p. 993.
Patai-"The Chemistry of the Carbon-Nitrogen Double Bond Interscience Publishers (1970)-p. 117.

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