Method for the treatment of cardiac and of vascular hypertrophy

Details Method for the treatment of cardiac and of vascular hypertrophy Method for the treatment of cardiac and of vascular hypertrophy

1990-08-09

1993-07-27

Lee, Lester L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 89, 514 91, 514 92, 514212, 514218, 514312, 514338, 5142235, 514249, 514255, 514278, 514318, 514343, 514409, 514422, 514423, 514616, 514693, A61E 3702, C07K 506

Patent

active

052310833

ABSTRACT:
The invention relates to a method for the treatment of cardiac and of vascular hypertrophy and hyperplasia by administration of angiotensin converting enzyme inhibitors. Administration of compounds of the formula I ##STR1## in which n is 1 or 2, R, R.sup.1, R.sup.2 and R.sup.3 are identical or different and each is hydrogen or an organic radical, and R.sup.4 and R.sup.5 form, together with the atoms carrying them, a mono-, bi- or tricyclic heterocyclic ring system, is preferred. The invention additionally relates to angiotensin converting enzyme inhibitors and to agents containing these for administration for the treatment of the abovementioned diseases.

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patent: 4602002 (1986-07-01), Patchett et al.
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