Precursors of 8-alkoxy-6,7-dihydro-5-methyl-9-fluoro-1-oxo-1H,5H

Details Precursors of 8-alkoxy-6,7-dihydro-5-methyl-9-fluoro-1-oxo-1H,5H Precursors of 8-alkoxy-6,7-dihydro-5-methyl-9-fluoro-1-oxo-1H,5H

1984-06-25

1986-02-04

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21520, C07D21500

Patent

active

045687501

ABSTRACT:
The compounds 5-bromo-6-fluoroquinaldine, 5-bromo-6-fluoro-1,2,3,4-tetrahydroquinaldine, 1-acetyl-5-bromo-6-fluoro-1,2,3,4-tetrahydroquinaldine and diethyl 2-[N-(6-fluoro-5-methoxy-1,2,3,4-tetrahydroquinaldinyl)]-methylenemalonate are intermediates for preparing antimicrobial 8-alkoxy-6,7-dihydro-5-methyl-9-fluoro-1-oxo-1H,5H-benzo[ij]-quinolizine-2 -carboxylic acids.

REFERENCES:
patent: 3896131 (1975-07-01), Gerster
Gyul'budagyan et al., CA 68: 87119w, Arm. Khim. Zh. 20(7), 522-525 (1967) Russ. (abstract).
Franchi et al., CA 68: 114400q, Farmaco, Ed. Sci. 22(11), 923-929 (1967) (Ital.) (abstract).
Murugesan et al., CA 91: 91532t, Synthesis 1979, (5), 352-354 (Eng.) (abstract).

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