Micro-reactor device for minute sample analysis

Details Micro-reactor device for minute sample analysis Micro-reactor device for minute sample analysis

1994-03-16

1996-01-02

Housel, James C.

Chemical apparatus and process disinfecting, deodorizing, preser

Analyzer, structured indicator, or manipulative laboratory...

Means for analyzing liquid or solid sample

422 50, 422 681, 422 81, 422 8205, 422108, 422116, 422145, 422213, 436 52, 436150, 436806, 204299R, G01N 2730, G01N 27447

Patent

active

054806143

ABSTRACT:
A minute sample analysis system includes a micro-reactor device, a quantitative measuring device, an analyzing device and a controller, whereby, when a very small amount of sample is handled, its dilution and loss can be suppressed to minimum level, and analyzing operations ranging from reaction with a reactive reagent to separation/detection of the sample can be consistently carried out efficiently. The micro-reactor device controls the solution, reactive reagent and sample flowing in the form of electroosmotic flow generated by high-voltage application under control of passage change-over switches. The quantitative measuring device measures the quantity of reactive sample received from the micro-reactor device and introduces the measured reactive sample into the analyzing device. The analyzing device optically detects components separated from the sample through electrophoresis. The above operations are generally controlled under by the controller.

REFERENCES:
patent: 4729947 (1988-03-01), Middendorf et al.
patent: 4882127 (1989-11-01), Rosenthal et al.
patent: 4908112 (1990-03-01), Pace
patent: 5100627 (1992-03-01), Buican et al.
patent: 5149661 (1992-09-01), Gjerde et al.
patent: 5171989 (1992-12-01), Williams et al.
Wu et al, Capillary Zone Electrophoresis . . . Amino Acids, Feb. 24, 1992, Talanta, vol. 39, No. 2, pp. 173-178.
Bruno et al, Thermo-Optical Absorption Detection in 25-.mu.m-i.d Capillaries-Capillary . . . Mixtures, Applied Spectroscopy, vol. 45, No. 3, 1991 pp. 462-467.
Yu et al, Attomole Amino Acid Determination by Capillary Zone Electrophoresis With Thermooptical Absorbance Detection Analytical Chemistry, vol. 61, No. 1, Jan. 1, 1989, pp. 37-40.
Sensors and Actuators B, vol. 10, pp. 107-116, 1993, D. Jed Harrison, et al., "Towards miniaturized electrophoresis and chemical analysis systems on silicon: an alternative to chemical sensors".
Anal. Chem., vol. 65, pp. 1481-1488, 1993, Kurt Seiler, et al., "Planar Glass Chips for Capillary Electrophoresis: Repetitive Sample Injection, Quantitation, and Separation Efficiency".
Anal. Chem., vol. 65, pp. 2637-2642, 1993, Carlo S. Effenhauser, et al., "Glass Chips for High-Speed Capillary Electrophoresis Separations with Submicrometer Plate Heights".
"A Gas Chromatographic Air Analyzer Fabricated on a Silicon Wafer", Terry et al, IEEE Transactions on Electron Devices, vol. ED-26, No. 12, Dec. 1979, pp. 1880-1886.

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