Method of monitoring patient compliance with medications prescri

Details Method of monitoring patient compliance with medications prescri Method of monitoring patient compliance with medications prescri

1994-05-24

1996-08-20

Alexander, Lyle A.

Chemistry: analytical and immunological testing

Nitrogen containing

Amine and quaternary ammonium

436171, 436808, 436901, G01N 3348

Patent

active

055478786

ABSTRACT:
A method of monitoring compliance of a patient that has been placed on a medication maintenance program with a prescribed medication dosage by determining a normalized urine methadone concentration. An unadulterated urine sample is obtained from the patient. The urine methadone concentration and urine specific gravity are measured. The normalized urine medication concentration is calculated as a function of the measured medication concentration in the urine and the urine specific gravity. The calculated normalized urine medication concentration is compared with an expected medication concentration value for the patient for the maintenance program prescribed to determine any significant differences therebetween as an indication of noncompliance.
Alternatively, a urinary-parameter normalized urine medication concentration is calculated as a function of the measured medication concentration in the urine, the urine specific gravity and at least one selected pharmacokinetic parameter of the medication. The calculated urinary-parameter normalized urine medication concentration is compared with an expected medication concentration value for an average compliant patient for the maintenance program prescribed to determine any significant differences therebetween as an indication of noncompliance.

REFERENCES:
patent: 2564247 (1951-08-01), Carson et al.
patent: 3856469 (1974-12-01), Schneider et al.
patent: 3901655 (1975-08-01), Shukla et al.
patent: 4104367 (1978-08-01), Gomez et al.
patent: 4196185 (1980-04-01), Focella et al.
patent: 5047329 (1991-09-01), Suzuki
patent: 5137692 (1992-08-01), Fritz
patent: 5179027 (1993-01-01), Fisher
Balabanova, et al "Methadone Distribution; Blood Cerebrospiral fluid; Urine and Organ Tissue": Embase No.: 92091431.
Nilsson, et al. "Effects of Urinary PHmH Disposition of Methadone in Man." Embase No. 82171209.

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