Production of 1,3-propanediol from glycerol by recombinant bacte

Details Production of 1,3-propanediol from glycerol by recombinant bacte Production of 1,3-propanediol from glycerol by recombinant bacte

1995-05-12

1997-05-27

Zitomer, Stephanie W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 221, 536 243, 4352523, 43525233, C07H 2102, C07H 2104, C12N 121

Patent

active

056333625

ABSTRACT:
A process is provided for the bioconversion of glycerol to 1,3-propanediol in which genes from a bacteria known to possess a diol dehydratase enzyme for 1,2-propanediol degradation are cloned into a bacterial host and the host is grown in the presence of glycerol; expression of the foreign genes in the host cell facilitates the enzymatic conversion of glycerol to 1,3-propanediol which is isolated from the culture.

REFERENCES:
patent: 4935554 (1990-06-01), Murphy et al.
patent: 4962027 (1990-10-01), Slininger et al.
patent: 5015789 (1991-05-01), Arntz et al.
patent: 5164309 (1992-11-01), Gottschalk et al.
patent: 5246843 (1993-09-01), Kasai et al.
patent: 5254467 (1993-10-01), Kretschmann et al.
Gibco-BRL catalog (1993-1994) pp. 9-5.
Daniel et al, (Apr. 1995), "Purification of 1,3-propanediol dehydrogenase from Citrobacter freundii and cloning, sequencing and overexpression of the corresponding gene in Escherichia coli", J. Bacteriol. 177(8):2151-2156.
Daniel et al, FEMS Microbiol. Lett., 100, 281-286 (1992).
Forage, R.G. et al, Bacteriology, 149(2), 413-419 (1982).
Jeter, R.M., J. Gen. Microbiology, 136, 887-896 (1990).
Tong, I-T et al, Appl. and Environmental Microbiology, 57(12), 3541-3546 (1991).
Ichikawa et al, J. Ferment. Technol., 63(2), 135-141 (1985).
Sprenger, G.A. et al, J. Gen. Microbiology, 135, 1255-1262 (1989).
Boenigk, R. et al, Appl. Microbiol. and Biotechnol., 38, 453-457 (1993).
Forsberg, C.W., Appl. Environ. Microbiol., 53(4), 639-643 (1987).
Zeng, A-P. et al, Enzyme Microb. Technol., 15, 770-779 (1993).
Bobik, T.A. et al, J. of Bacteriol., 174(7), 2253-2266 (1992).
Hartmanis, M.G.N. et al, Archives of Biochem. and Biophysics, 245(1), 144-152 (1986).
Tobimatsu, T. et al, J. Biol. Chem., 270(13), 7142-7148 (1995).

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