Glucagon-like insulinotropic peptides, compositions and methods

Details Glucagon-like insulinotropic peptides, compositions and methods Glucagon-like insulinotropic peptides, compositions and methods

1995-03-21

1998-01-06

Hutzell, Paula K.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530308, 530324, A61K 3826, C07K 14605

Patent

active

057054835

ABSTRACT:
The present invention provides novel complexes consisting of certain GLP-1 molecules associated with a divalent metal cation that is capable of co-precipitating with a GLP-1 molecule. Pharmaceutical compositions and methods of using such complexes for enhancing the expression of insulin in B-type islet cells is claimed, as is a method for treating maturity onset diabetes mellitus in mammals, particularly humans.

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