Controlled release N-substituted pyrrolidone esters and process

Details Controlled release N-substituted pyrrolidone esters and process Controlled release N-substituted pyrrolidone esters and process

1991-03-20

1993-04-27

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548413, C07D20727, A61K 3140

Patent

active

052063860

ABSTRACT:
N-substituted cyclic lactam esters are made from biologically active organic acids and N-haloalkyl substituted cyclic lactam, preferably N-chloromethyl pyrrolidone. Such esters provide slow release of the organic acids in situ through slow hydrolysis of the ester to release the organic acid and the N-alkyl substituted cyclic lactam. The esters are useable for delivering a large variety of biologically active organic acids in slow release fashion to target organisms and promote effective long term therapeutic treatment. In particular, an ester made from acetyl salicyclic acid and chloromethyl pyrrolidone provides a vehicle for dermal penetration and slow release of aspirin for long term treatment.

REFERENCES:
patent: 4162325 (1979-07-01), Rodriquez et al.

Affiliated with

Also associated with

Rating

Controlled release N-substituted pyrrolidone esters and process does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Controlled release N-substituted pyrrolidone esters and process , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Controlled release N-substituted pyrrolidone esters and process will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2328607