Method for producing recombinant proteins and host cells used th

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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43525411, 435 693, 435 694, 435 695, 435 6951, 435 6952, 435 696, 435 697, 435 698, 435 699, 435 711, 435189, 435192, 435198, 435201, 435226, 435227, 4352542, 4352551, 435911, C12N 1106, C12N 119, C12N 1563, C12N 1581

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056331460

ABSTRACT:
Novel genetically engineered yeast strains of genus Kluyveromyces lactis, their preparation, and the use thereof for producing recombinant proteins, are described.

REFERENCES:
Bio/Technology 8:135-9, 1990, van den Berg, van der Laken, van Ooyen, Renniers, Rietveld et al., Kluyveromyces as a Host for Heterologous Gene Expression: Expression and Secretion of Prochymosin, English Original.
J. Cell. Biochem. Suppl. 14C:68, Abst. H402, 1990, Yeh, Fleer, Chen, Maury, Faulconnier et al., pKD1-Based Secretion Vectors for the Production of Human Recombinant Proteins in Kluyveromyces Yeasts, English Original.
Yeast 6 (Special Issue):S449, 1990, Fleer, Yeh, Becquart, Amellal, Maury et al., pKD1-Based Multi-Copy Vectors Mediate High Level Secretion of Human Serum Albumin (HSA) from . . . , English Original.
WO83/04050 May 19, 1983, Hollenberg, Das, De Leeuw, van den Berg, Cloning System for Kluyveromyces Species, English Original.
EP0096910 May 19, 1983 Edens, Ledeboer, Verrips, Van Den Berg, Yeast of the genus kluyveromyces modified for the expression of preprothaumatin or its various . . . English Original.
EP0241435 Mar. 25, 1987 Falcone, Fukuhara, Frontali, Vectors for the cloning and expression of heterologous genes in yeast and the yeast strains transformed by said . . . English Original.
EP0301670 Jul. 28, 1988 van den Berg, van Ooyen, Rietveld, Kluyveromyces as a host strain, English Original.
EP0361991, Aug. 4, 1989, Fleer, Fukuhara, Yeh, Method for the microbiological preparation of human serum albumin and other heterologous proteins, English Original.

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