Method for simultaneously detecting multiple mutations in a DNA

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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536 243, C12Q 168

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056331347

ABSTRACT:
The invention provides a rapid, cost-effective process for simultaneously testing large numbers of individuals for the presence or absence of multiple mutaitons in one gene or multiple genes using allele specific oligonucleotide (ASO) probes in the presence of a quaternary ammonium salt which eliminates disparities in the melting temperatures of the ASO used.

REFERENCES:
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