Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1991-05-14
1993-04-27
Friedman, S. J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514221, A61U 3155
Patent
active
052062376
ABSTRACT:
Pharmaceutical compositions containing benzodiazepines of the formula: ##STR1## are disclosed which are useful in the treatment of panic disorder or anxiety disorder.
REFERENCES:
patent: 852478 (1892-03-01), Freidinger et al.
patent: 4755508 (1982-03-01), Freidinger et al.
patent: 4820834 (1989-04-01), Evan et al.
Bradwejn, et al., Enhanced Sensitivity to Cholecystokinin Tetrapeptide in Panic Disorder, Soc. Neurosci. Abstr. 14(1), p. 291, (1988).
de Montigny, Cholecystokinin Tetrapeptide Induces Panic Attacks in Healthy Volunteers, soc. Neurosci. Abstr. 14(1), p. 291, (1988).
Bradwejn, et al., Benzodiazepines Antagonize Cholecystokinin--Induced Activation of Rat. Hippocampal, Nature 312, p. 22, (1984).
de Montigny, Cholecystokinin Tetrapeptide Induces Panic-Like Attacks in Healthy Volunteers, Arch. Gen. Psychiatry, 46, (1989).
Dourish, et al., Morphine Induced Analgesia in the rat Paw Pressure Test is Blocked by CCK and Enhanced by the CCK Antagonist MK-329, Eur. Jour. Pharm. 147, No. 3, pp. 469-472, (1988).
Bouthillier, et al., Long-term Benzodiazepine Treatment Reduces Neuronal Responsiveness to Cholecystokinin: an Electrophysiological Study in the Rat, Eur. Jour. Pharm. 151, No. 1, pp. 135-138, (1988).
M. A. Silverman, Cholecystokinin Receptor Antagonists: A Review Amer. Mour. Gast., vol. 82, pp. 703-708 (1987).
Bock Mark G.
Evans Ben E.
Freidinger Roger M.
Daniel Mark R.
DiPrima Joseph F.
Friedman S. J.
Merck & Co. , Inc.
LandOfFree
Benzodiazepine analogs does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Benzodiazepine analogs, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Benzodiazepine analogs will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2327171