Preparation of angiotensin-converting enzyme inhibitors

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D48704

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048311570

ABSTRACT:
Novel compounds with angiotensin-converting enzyme inhibitory activity are disclosed. Such compounds are useful in the treatment of cardiovascular disorders, especially hypertension and congestive heart failure, and are useful in the treatment of glaucoma. Also disclosed is a novel process for preparing intermediates useful in the preparation of the claimed compounds.

REFERENCES:
patent: 4727160 (1988-02-01), Teetz et al.
R. Bonnet et al, J. Chem. Soc., 2087 (1959).
M. Mitzlaff et al, Liebigs Ann. Chem., 1713 (1978).
V. Asher et al., Tetrahedron Lett., 141 (1981).
G. B. R. deGraaf et al., Rec. Trav. Chem., 81,786 (1962).
K. Kariyone, Chem. Pharm. Bull., 8, 1110 (1960).
K. Kariyone, Chem. Abstr., 53, 21940 (1959).
D. Sieback and D. Enders, Angew. Chem. Internat., Edit 14,15 (1975).
A. G. Anderson et al., J. Org. Chem., 43,55 (1978).
H. Booth et al., J. Chem. Soc., 1050 (1959).
F. E. King et al., J. Chem. Soc., 250 (1953).
E. D. Bergman et al., J. Amer. Chem. Soc., 78,1482 (1956).
H. T. Nagasawa et al., J. Med. Chem., 14,501 (1971).
J. A. Elberling et al., J. Heterocycl. Chem., 9,411 (1971).
R. Henning et al., Tetrahedron Lett., 24, 5339 (1984).
S. V. Kessar et al, J. Indian Chem. Soc., 40, 655 (1963).
W. C. Francis et al., J. Amer. Chem. Soc., 80, 6238 (1958).
R. J. Wineman et al., J. Amer. Chem. Soc., 80, 6233 (1958).
E. D. Bergman et al., J. Amer. Chem. Soc., 80, 3135 (1958).

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