Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1988-09-28
1989-05-16
Springer, David B.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D48704
Patent
active
048311570
ABSTRACT:
Novel compounds with angiotensin-converting enzyme inhibitory activity are disclosed. Such compounds are useful in the treatment of cardiovascular disorders, especially hypertension and congestive heart failure, and are useful in the treatment of glaucoma. Also disclosed is a novel process for preparing intermediates useful in the preparation of the claimed compounds.
REFERENCES:
patent: 4727160 (1988-02-01), Teetz et al.
R. Bonnet et al, J. Chem. Soc., 2087 (1959).
M. Mitzlaff et al, Liebigs Ann. Chem., 1713 (1978).
V. Asher et al., Tetrahedron Lett., 141 (1981).
G. B. R. deGraaf et al., Rec. Trav. Chem., 81,786 (1962).
K. Kariyone, Chem. Pharm. Bull., 8, 1110 (1960).
K. Kariyone, Chem. Abstr., 53, 21940 (1959).
D. Sieback and D. Enders, Angew. Chem. Internat., Edit 14,15 (1975).
A. G. Anderson et al., J. Org. Chem., 43,55 (1978).
H. Booth et al., J. Chem. Soc., 1050 (1959).
F. E. King et al., J. Chem. Soc., 250 (1953).
E. D. Bergman et al., J. Amer. Chem. Soc., 78,1482 (1956).
H. T. Nagasawa et al., J. Med. Chem., 14,501 (1971).
J. A. Elberling et al., J. Heterocycl. Chem., 9,411 (1971).
R. Henning et al., Tetrahedron Lett., 24, 5339 (1984).
S. V. Kessar et al, J. Indian Chem. Soc., 40, 655 (1963).
W. C. Francis et al., J. Amer. Chem. Soc., 80, 6238 (1958).
R. J. Wineman et al., J. Amer. Chem. Soc., 80, 6233 (1958).
E. D. Bergman et al., J. Amer. Chem. Soc., 80, 3135 (1958).
Gold Elijah H.
Neustadt Bernard R.
Smith Elizabeth M.
Magatti Anita W.
Miller Stephen I.
Rosen Gerald S.
Schering Corporation
Springer David B.
LandOfFree
Preparation of angiotensin-converting enzyme inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Preparation of angiotensin-converting enzyme inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of angiotensin-converting enzyme inhibitors will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2323914