Preparation of pharmaceutical grade amino acid chelates

Chemistry: electrical and wave energy – Processes and products

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204 59QM, 556 50, 556134, 556148, C25D 102

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active

048307165

ABSTRACT:
Pharmaceutical grade amino acid chelates, free of interfering anions, are made by reacting an amino acid ligand with a metal member selected from the group consisting of elemental metals, metal oxides, metal hydroxides and metal carbonates in an aqueous environment wherein the ligand to metal mole ratio is at least 2:1 and recovering the amino acid chelate from said aqueous environment by means of spray or drum drying. The reaction may be carried out in the presence of non-interfering anions such as anions from citric acid, ascorbic acid, acetic acid, carbonic acid and ammonium and alkali metal salts thereof.

REFERENCES:
patent: 4172072 (1979-10-01), Ashmead
patent: 4216143 (1980-08-01), Ashmead
patent: 4216144 (1980-08-01), Ashmead
patent: 4448716 (1984-05-01), Tsau
patent: 4599152 (1986-07-01), Ashmead

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