Process for preparing alpha-arylalkanoic acids

Details Process for preparing alpha-arylalkanoic acids Process for preparing alpha-arylalkanoic acids

1983-08-03

1985-08-13

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548217, 548444, 548562, 549 79, 560 55, 560 56, 560105, 562465, 562466, 562496, C07C 67333

Patent

active

045351660

ABSTRACT:
Rearrangement of alpha-halo-alkylarylketals in neutral or weakly alkaline conditions and in the presence of a polar-protic medium and subsequent hydrolysis of the thus obtained esters, in the same reaction medium, to afford the corresponding alpha-arylalkanoic acids or their salts which are particularly useful as anti-inflammatory, analgesic and antipyretic agents.

REFERENCES:
patent: 4414405 (1983-11-01), Giordano
March, Advanced Organic Chemistry, pp. 991-995, (1977).

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