Process for medical implant of cross-linked ultrahigh molecular

Details Process for medical implant of cross-linked ultrahigh molecular Process for medical implant of cross-linked ultrahigh molecular

1997-08-15

2000-01-25

Truong, Duc

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Compositions to be polymerized by wave energy wherein said...

522184, 522189, 522911, 522912, 528503, C08J 328

Patent

active

060179759

ABSTRACT:
A medical implant of ultrahigh molecular weight polyethylene having an improved balance of wear properties and oxidation resistance is prepared by irradiating a preform of ultrahigh molecular weight polyethylene, annealing the irradiated preform in the absence of oxygen to a temperature at or above the onset of melting temperature, and forming an implant from the stabilized cross-linked polymer. Implants prepared according to the process of the present invention have comparable oxidation resistance and superior wear performance compared to unirradiated ultrahigh molecular weight polyethylene.

REFERENCES:
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patent: 5449745 (1995-09-01), Sun et al.
patent: 5543471 (1996-08-01), Sun et al.
Streicher, "Ionizing irradiation for sterilization and modification of high molecular weight polyethylenes", Plastics and Rubber Processing and Applications, vol. 10, No. 4, pp. 221-229, 1988.
Streicher, "Influence of Ionizing Irradiation in Air and Nitrogen for Sterilization of Surgical Grade Polyethylene for Implants", Radiat. Phys. Chem, vol. 31, Nos. 4-6, pp. 693-698, 1988.
Roe et al., "Effect of radiation sterilization and aging on ultrahigh molecular weight polyethylene", Journal of Biomedical Materials Research, vol. 15, pp. 209-230, 1981.
Kurth et al., "Effect of radiation Sterilization on UHMW-Polyethylene", Third World Biomaterials Congress, p. 589, Apr. 21-25, 1988.
Plessis et al., "The Improvement of Polyethylene Prostheses Through Radiation Crosslinking", Radiat. Phys. Chem., vol. 9, pp. 647-652, 1977.
Streicher, "The Behavior of UHMW-PE when Subjected to Sterilization by Ionizing Radiation", Ultra-High, Molecular Weight Polyethylene as Biomaterial in Orthopedic Surgery, pp. 66-73, 1990.
Grobbelaar et al., "The Radiation Improvement of Polyethylene Prostheses", The Journal of Bone and Joint Surgery, vol. 60-B, No. 3, pp. 370-374, Aug. 1978.

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