Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-01-20
2000-01-25
Davis, Zinna Northington
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514346, 546255, 546292, C07D21302, A61K 31445
Patent
active
060179341
ABSTRACT:
A compound which inhibits human thrombin and where has the structure ##STR1##
REFERENCES:
patent: 5260307 (1993-11-01), Ackermann et al.
patent: 5405854 (1995-04-01), Ackermann et al.
patent: 5510369 (1996-04-01), Lumma et al.
Bernstein et al., J. Med. Chem., "Nonpeptidic Inhibitors of Human Leukocyte Elastase. 3.1 Design, Synthesis, X-ray Crystallographic Analysis, . . . ", vol. 37, pp. 3313-3326 (1994).
Edwards et al., J. Am. Chem. Soc., "Design, Synthesis, and Kinetic Evaluation of a Unique Class of Elastase Inhibitors, . . . ", vol. 114(5), pp. 1854-1863 (1992).
Brown et al., J. Med. Chem., "Design of Orally Active, Non-Peptidic Inhibitors of Human Leukocyte Elastase", vol. 37(9), pp. 1259-1261 (1994).
Coburn Craig
Lyle Terry A.
Sanderson Philip E.
Davis Zinna Northington
Merck & Co. , Inc.
Parr Richard S.
Winokur Melvin
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