Phenyl substituted prostaglandins-C-type analogs

Details Phenyl substituted prostaglandins-C-type analogs Phenyl substituted prostaglandins-C-type analogs

1973-11-12

1976-11-23

Killos, Paul J.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260240R, 2603433R, 2603457, 2603458, 2603473, 2603474, 2603475, 2604482Q, 2604482R, 260468D, 260514D, 260520B, 424305, 424308, C07C 6976

Patent

active

039936864

ABSTRACT:
Process for the total synthesis of 11,12-unsaturated prostaglandin compounds, i.e., prostaglandin C.sub.2 -type compounds and analogs, and to certain novel compounds and intermediates produced thereby. The compounds produced by said process are useful as vasodepressors and antisecretory agents, and in managing cases of renal disfunction.

REFERENCES:
patent: 3678092 (1972-07-01), Finch
Jones, Brit. J. Pharmacol. 45 144p-145p (1972).
Jones, Biochem. Biophys. Acta. 280 (1972) 588-601.

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