Pyrimidine 2,4-dioxamate compounds and pharmaceutical compositio

Details Pyrimidine 2,4-dioxamate compounds and pharmaceutical compositio Pyrimidine 2,4-dioxamate compounds and pharmaceutical compositio

Filed on

1987-04-03

Date issued

1988-03-08

Examiner

Ramsuer, Robert W.

Patent Class

Drug, bio-affecting and body treating compositions

SubClass

Designated organic active ingredient containing

SubSubClass

Heterocyclic carbon compounds containing a hetero ring...

Other Related Categories

514233, 514234, 514236, 514252, 514272, 514275, 540601, 540467, 540470, 540481, 544122, 544295, 544320, 544321, 544323, A61K 31505, A61K 31535, C07D23948, C07D41304

Type

Patent

Status

active

Patent number

047299959

Description

ABSTRACT:
Novel pyrimidine compounds of the formula: ##STR1## wherein R.sub.1 and R.sub.1 ' are each hydrogen atom, a lower alkyl, benzyl, an alkali metal, or ammonium; R.sub.2 is hydrogen atom, a halogen atom, a lower alkyl, a lower alkoxy, an aryl, a group of the formula: ##STR2## (wherein R.sub.3 and R.sub.4 are each hydrogen atom, a lower alkyl, or an aryl), or a group of the formula: ##STR3## [wherein R.sub.5 and R.sub.6 are each an alkylene having 1 to 3 carbon atoms, and X is oxygen atom, methylene, or a group of the formula: >N-Y (wherein Y is hydrogen atom, a lower alkyl, benzyl, or an aryl)], which have excellent antiallergic activities and are useful for the prophylaxis and treatment of various allergic diseases, and a pharmaceutical composition containing said pyrimidine compound as an active ingredient.

REFERENCES:
Bazzano, International Publication Number WO86/00616, Jan. 30, 1986.

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