Receptor activator of NF-.kappa.B

Details Receptor activator of NF-.kappa.B Receptor activator of NF-.kappa.B

1997-12-22

2000-01-25

Kemmerer, Elizabeth

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 701, 4353201, 435325, 4352351, 435 231, 435 2431, 4352523, 4351723, 536 231, 536 2431, 530350, C07H 2104, C12N 1512, C12N 1563

Patent

active

060177292

ABSTRACT:
Isolated receptors, DNAs encoding such receptors, and pharmaceutical compositions made therefrom, are disclosed. The isolated receptors can be used to regulate an immune response. The receptors are also useful in screening for inhibitors thereof.

REFERENCES:
Yasuda et al., Proc. Natl. Acad. Sci. 95:3597; 1998.
Suda et al., Endocr. Rev. 13:66; 1992.
Suda et al., Bone 17:87S; 1995.
Suda et al., in Endocrine Review Monographs. eds. Bikle, D.D. & Negrovilar, A. (Endocrine Soc., Bethesda), vol. 4, pp. 266-270; 1995.
Lacey et al., Cell 93:165; 1998.
Anderson et al., Nature 390:175; 1997.
EMBL Database entry HS421358; Accession No. W74421, Jun. 21, 1996; Hillier et al.: Homo sapiens cDNA clone 346544 contains Alu repetitive element.
GenEmbl Database Accesion No. X15271, Locus.HSTRGV3F, Human T-cell receptor gamma. Lefranc, M.P.
George et al., Current Methods in Sequence Comparison and Analysis, selected methods and applications. Edited by David H. Schlesinger, alan R. Liss, Inc., New York, pp 124-129 1988.
Embl-est Database Accession No.R03478, yq16f06.rl Homo Sapian cDNA clone 197123 5' sequence. Submitted by Hillier et al. Aug. 29, 1995.

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