Process for the preparation of aryl (or heteroaryl) piperazinylb

Details Process for the preparation of aryl (or heteroaryl) piperazinylb Process for the preparation of aryl (or heteroaryl) piperazinylb

1992-03-06

1993-07-13

Morris, Patricia L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544362, 544366, 544368, 544370, 544371, 544372, 544373, C07D40314, C07D47104, C07D41714

Patent

active

052274861

ABSTRACT:
The present invention relates to a process for the preparation of aryl (or heteroaryl) piperazinyl-butylazole derivatives corresponding to the general formula I ##STR1## in which Ar denotes a nitrogenous or other aromatic radical chosen from differently substituted aryls, differently substituted 2-pyrimidine, 2-N-methyl-imidazole and 3-(1,2-benzisothiazole)

REFERENCES:
patent: 5128343 (1992-07-01), Pinol et al.
Chemical Abstracts, vol. 115, No. 17, Oct. 1991; Malinka "Synthesis and 2H-2(4-substituted-1-piperazinylalkyl)-4,6-dimethyl-3-oxo-2,3-dihydroisoth iazolo(5,4-b)pyridines" & Acta Pol. Pharm. 1990, vol. 47, Nos. 1-2 CA 115:183160n.
Chemical Abstracts, vol. 70, No. 13, Nov. 31, 1969; Stogryn "Antimalarials related to 2-bromo-4,5-dimethoxy-N,N-bis(diethylaminoethyl)aniline" & J. Med. Chem. 1969, vol. 12, No. 1 CA 70:57766d.

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