Thieno[2,3-b] pyrrole compounds and analgesic use thereof

Details Thieno[2,3-b] pyrrole compounds and analgesic use thereof Thieno[2,3-b] pyrrole compounds and analgesic use thereof

1983-12-12

1986-08-26

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548453, C07D49504, A61K 3138

Patent

active

046083847

ABSTRACT:
New thieno[2,3-b] pyrrole compounds of the formula: ##STR1## in which: R.sub.1 is hydrogen or lower alkyl,

REFERENCES:
Burger's Medicinal Chemistry, Fourth Edition, Part III, pp. 703-704 and 1217-1218.
Br. J. Pharmacol. (1973), 49, pp. 86-97.
J. Pharmacol. Exp. Therap. (1964), 80, pp. 300-307.
J. Pharmacol. Exp. Therap. (1964), 125, pp. 237-240.
Evaluation of Drug Activity: Pharmacometrics, Editors: D. R. Laurence-A. L. Bacharach (Academic Press) (1964), vol. 1, pp. 183-203.
La Belle, A. and Tislow, R., J. Pharmacol. Exp. Ther. (1950), 98, 19.
L. F. Sancilio, J. Pharmacol. Exp. Ther. (1969), 168, 199-204.
Winter, C. A., Riseley, E. A., and Nuss, G. W., J. Pharmacol. Exp. Ther. (1963), 141, 369-376.
Chen, I. Y. P. and Beekman, H., Science (1951), 113, 631.
Flower, R. J., Chung, H. S. and Cushman, D. W., Prostaglandins (1973), (4), 325-337.

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