N1-substituted 1H-1,2,3-triazolo[4,5,-D]pyrimidines, a process f

Details N1-substituted 1H-1,2,3-triazolo[4,5,-D]pyrimidines, a process f N1-substituted 1H-1,2,3-triazolo[4,5,-D]pyrimidines, a process f

1993-09-23

1995-10-10

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

514258, 544224, 544254, A61K 31505, C07D23900

Patent

active

054570913

ABSTRACT:
N1-Substituted 1H-1,2,3-triazolo[4,5-d]pyrimidine compounds of the formula I ##STR1## in which the substituents X, Y, R.sup.1, R.sup.2 and R.sup.3 have the meanings recited in the specification, are described as pharmaceutical compositions containing them and processes for their preparation. The compounds are effective antiviral agents.

REFERENCES:
patent: 4027025 (1977-05-01), Schaeffer
patent: 4199574 (1980-04-01), Schaeffer
patent: 4268672 (1981-05-01), Vince
patent: 4294831 (1981-10-01), Schaeffer
patent: 4323573 (1982-04-01), Schaeffer
patent: 4360422 (1982-11-01), Oka et al.
patent: 4543255 (1985-09-01), Shealy et al.
patent: 4714701 (1987-12-01), Beauchamp
patent: 4728736 (1988-03-01), Shealy et al.
patent: 4742064 (1988-05-01), Vince
patent: 5225550 (1993-07-01), Jahne
Beauchamp et al., Journal of Medicinal Chemistry, 1985, 28(8): 982-987.
K. Ogilvie et al., "Synthesis of a Purine Acyclonucleoside Series Having Pronounced Antiviral Activity. The Glyceropurines," Can. J. Chem. 62, pp. 241-252 (1984).
C. Chu et al., "Chemistry and Antiviral Activities of Acyclonucleosides," J. Heterocyclic Chem. 23, pp. 289-319 (1986).
J. Stein et al., "Inhibition of Human Purine Nucleoside Phosphorylase By Acyclic Nucleosides and Nucleotides," Biochem. Pharmacol. 36, pp. 1237-1244 (1987).
CA 53, 1389g (1959).
L. Beauchamp et al., "Modifications on the Heterocyclic Base of Acyclovir: Synthesis and Antiviral Properties," J. Med. Chem. 28, pp. 982-987 (1985).
A. Colautti et al., "Zusammenfassung," Chemical Abstracts, vol. 75, No. 13, abstract No. 88567x, cite 710-717 (1971).
F. Seela et al., "Zusammenfassung," Chemical Abstracts, vol. 118, No. 7, abstract No. 60018b, cite 1885-1896 (1993).

Affiliated with

Also associated with

Rating

N1-substituted 1H-1,2,3-triazolo[4,5,-D]pyrimidines, a process f does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with N1-substituted 1H-1,2,3-triazolo[4,5,-D]pyrimidines, a process f, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and N1-substituted 1H-1,2,3-triazolo[4,5,-D]pyrimidines, a process f will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2310465