Phosphonoalkylquinolin-2-ones as novel antagonists of non-NMDA i

Details Phosphonoalkylquinolin-2-ones as novel antagonists of non-NMDA i Phosphonoalkylquinolin-2-ones as novel antagonists of non-NMDA i

1994-06-14

1996-04-23

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

546 21, 546 23, C07D215227, C07D21518, C07D21538, A61K 3147

Patent

active

055103383

ABSTRACT:
The present invention pertains to antagonists of excitatory amino acid receptors, their method of preparation as well as compositions pertaining to them, which have the general formula: ##STR1## wherein n is 0, 1, 2, or 3; R1 and R.sub.2 are selected from the group consisting of hydrogen, halogen, halomethyl, nitro, amino, alkoxy, hydroxyl, hydroxymethyl, C.sub.1 to C.sub.6 lower alkyl and C.sub.7 to C.sub.12 higher alkyl, aryl and aralkyl; and the pharmaceutically acceptable salts thereof.

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