Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1977-04-01
1979-05-29
Reamer, James H.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
C07C 8506, C07C 8504
Patent
active
041566939
ABSTRACT:
Novel linear, unbranched, non-cross-linked polymers particularly poly-[{methyl-(3-trimethylammoniopropyl)iminio}trimethylene dihalide] are prepared by the polymerization of the novel monomer, 3-[N'-(3-halopropyl)-N'-methylamino]-N,N,N-trimethyl-1-propanaminium halide, or an acid addition salt thereof preferably in an oxygen excluded environment, e.g., under nitrogen or argon. The polymer, especially after modification of terminal groups, is an excellent oral anticholesterolemic.
REFERENCES:
patent: 2163181 (1939-06-01), Ulrich et al.
patent: 3176040 (1965-03-01), Wilkinson et al.
patent: 3905968 (1975-09-01), Schneider
Piper et al., J. of Med. Chem., vol. 18 (8), pp. 803-812 (1975).
Fieser et al., Reagents for Organic Synthesis, pp. 1158-1163 (1965).
Merck & Co. , Inc.
Patton Walter
Reamer James H.
Westlake, Jr. Harry E.
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