Novel polyol ether compounds, process preparing the compounds, a

Details Novel polyol ether compounds, process preparing the compounds, a Novel polyol ether compounds, process preparing the compounds, a

1984-07-16

1986-03-18

Mars, Howard T.

Drug, bio-affecting and body treating compositions

Designated organic nonactive ingredient containing other...

Aftertreated solid synthetic organic polymer

568675, 568679, 568680, 568623, A61K 700, C07C 4310, C07C 4314

Patent

active

045769672

ABSTRACT:
Triglycerine monoalkyl ethers of the general formula (I), which are novel polyol ether compounds, ##STR1## in which R represents a saturated or unsaturated, linear or branched fatty hydrocarbon group having from 8 to 24 carbon atoms.
The ethers (I) of the present invention are prepared from firstly subjecting 1,3-bis-o-(2,3-o-isopropylideneglyceryl)glycerine (II) and an etherifying agent (IV) to Williamson's ether synthesis reaction, and the resulting 1,3-bis-o-(2,3-o-isopropylideneglyceryl)-2-o-alkylglycerine (III) is subsequently subjected to hydrolysis.
The ethers according to the invention are chemically stable because no linkages susceptible to decomposition, e.g. ester bond, are contained in the molecular structure of the ethers. Moreover, the ethers give a reduced degree of stimulus to the skin and have the surface activity, so that they are useful as an emulsifier, oil (emolient), humectant, thickener and particularly as a component of cosmetics.

REFERENCES:
patent: 2258892 (1941-10-01), Harris
patent: 3666671 (1972-05-01), Kalopissis et al.
patent: 4298764 (1981-11-01), Berkowitz
patent: 4465866 (1984-08-01), Takaishi et al.

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