Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-01-30
1993-08-31
Morris, Patricia L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514340, 514383, 546276, 548252, 5482642, 5482644, A61K 3141, A61K 31435, C07D40312, C07D40314
Patent
active
052409538
ABSTRACT:
This invention relates to novel bis-biphenyl substituted 3-mercapto-1,2,4-tetrazoles and to pharmaceutically acceptable salts thereof.
The compounds are angiotensin II receptor antagonists, and are useful in treating hypertension (lowering high blood pressure), congestive heart failure, elevated ocular pressure, cerebral stroke, angina, cardiac insufficiency, myocardial infection or diabetic nephropathy.
The invention also relates to pharmaceutical composition comprising a compound of the invention, a method of treating a physiological condition in a mammal that is mediated by angiotensin II which comprises administering to the mammal an effective amount of a compound of the invention, and novel processes for preparing the compounds of the invention.
REFERENCES:
patent: 5093346 (1992-03-01), Carini et al.
Bandurco Victor T.
Murray William V.
Schwender Charles F.
Wachter Michael P.
Morris Patricia L.
Ortho Pharmaceutical Corporation
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