Diazabicyclononene antibacterials

Details Diazabicyclononene antibacterials Diazabicyclononene antibacterials

1983-09-28

1986-01-21

Berch, Mark L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D51304

Patent

active

045656550

ABSTRACT:
Fused 4,7-.beta.-lactam bicyclic antibacterials, namely 8-acylamino-4-anilino-9-oxo-6-thia-1,3-diazabicyclo[5.2.0]non-3-ene-2-carb oxylic acids, and the esters, salts and sulfoxides thereof, are provided. The compounds as esters are prepared by process comprising heating a 3-azido-3-cephem ester with aniline, a substituted aniline, or an N-(C.sub.1 -C.sub.3 alkyl) derivative thereof.

REFERENCES:
patent: 4064343 (1977-12-01), Chauvette

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