Imidazol-1-yl propane derivatives

Details Imidazol-1-yl propane derivatives Imidazol-1-yl propane derivatives

1976-03-08

1977-07-19

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

260309, 260348R, 260609F, A61K 31415, C07D23360

Patent

active

040369730

ABSTRACT:
Compounds of the formula ##STR1## wherein one of R.sup.1 and R.sup.2 is alkyl or the group ##STR2## IN WHICH N IS 0 TO 3 AND THE OTHER OF R.sup.1 and R.sup.2 is benzyl, substituted benzyl, phenyl or substituted phenyl, said substituted benzyl and substituted phenyl substituted on the phenyl ring with one or more substituents independently selected from the group consisting of halo, lower alkyl and trifluoromethyl; X and Y are independently oxygen or sulfur with the proviso that Y is not oxygen when R.sup.2 is phenyl or substituted phenyl; and the antimicrobial acid addition salts thereof are useful as antifungal, antibacterial and antiprotozoal agents.

REFERENCES:
patent: 3531494 (1970-09-01), Adolphi et al.
patent: 3940415 (1976-02-01), Buchel et al.

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