Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1996-08-23
1998-03-24
O'Sullivan, Peter
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514619, 514621, 514821, 514824, 514866, 514893, 558412, 558413, 558415, 564134, 564139, 564142, 564162, 564163, 564166, 564167, C07C27922, C07C27708, A61K 31155
Patent
active
057313512
ABSTRACT:
Alkyl-benzoylguanidines of the formula I ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 have the meanings given, and physiologically acceptable salts thereof show antiarrhythmic properties and act as inhibitors of the cellular Na.sup.+ /H.sup.+ antiporter.
REFERENCES:
patent: 5571842 (1996-11-01), Kleemann et al.
Kuno et al., "Benzoylguanidine Derivatives as Medicaments Inhiibiting Cellular Na +/H+ exchange", Chem. Abst. vol. 125, No. 3, 1996.
Baumgarth Manfred
Beier Norbert
Gericke Rolf
Minck Klaus-Otto
Merck Patent Gesellschaft mit beschrankter Haftung
O'Sullivan Peter
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