Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1995-10-24
1998-03-24
Grumbling, Matthew V.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
5142355, 5142358, 514252, 514255, 514315, 514316, 514318, 514320, 514329, 514341, 514342, 514343, 544 581, 544 59, 544162, 544358, 544360, 544382, 544386, 546193, 546194, 546195, 546196, 546197, 546198, 546199, 546200, C07D40302, C07D40102, A61K 31535, A61K 3154
Patent
active
057313091
ABSTRACT:
Compounds of formula I ##STR1## wherein Q.sup.1, Q.sup.2, Q.sup.3, and Q.sup.4 have any of the meanings given in the specification, their N-oxides, and their pharmaceutically acceptable salts are nonpeptide antagonists of SP and NKA are useful for the treatment of asthma, etc. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of formula I and intermediates.
REFERENCES:
Edmonds-Alt et al., Bioorg. Med. Chem. Lett, 3(5) 425-430, 1993.
Bernstein Peter R.
Miller Scott C.
Darkes Paul R.
Grumbling Matthew V.
Harris Robert J.
Zeneca Limited
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