Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1990-04-13
1992-03-10
Lee, Mary C.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
548110, 548147, 548216, 548218, C07D49804, C07D51304
Patent
active
050951181
ABSTRACT:
D-(+)-biotin can be prepared from optically active hydantoins of the formula I ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, X and Y have the meaning given in Patent claim 1, in a simple, stereospecific manner. Furthermore bicyclic nitriles of the formula XI ##STR2## wherein R.sup.1, R.sup.2, R.sup.3, X and Y have the meaning given represent precious intermediate products and educts of a multitude of possibilities to synthesize optically active D-(+)-biotin.
REFERENCES:
patent: 4468516 (1984-08-01), Volkmann
patent: 4772717 (1988-09-01), Volkmann
Poetsch et al., Chemical Abstracts, vol. 108, entry 112041u, (1988).
Casutt Michael
Poetsch Eike
Lee Mary C.
Merck Patent Gesellschaft mit beschrankter Haftung
Miltenberger Lenora
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