Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
1979-12-20
1980-12-09
Rollins, Alton D.
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
260239BD, C07D23904, C07D24506
Patent
active
042386101
ABSTRACT:
Novel intermediates of the formula ##STR1## wherein X and Y are hydrogen, halogen or trifluoromethyl and R.sub.1 is hydrogen or lower alkyl are presented.
Also disclosed is a process leading to the intermediates and their conversion to imidazobenzodiazepines, compounds of pharmacological activity.
REFERENCES:
patent: 3215694 (1965-11-01), Rachlin et al.
patent: 3480629 (1969-11-01), Ott
patent: 3523972 (1970-08-01), Field et al.
patent: 4118386 (1978-10-01), Walser
patent: 4125726 (1978-11-01), Walser et al.
Field et al., J. Am. Chem. Soc., vol. 89, pp. 332-338 (1967).
Hester, J. Org. Chem., vol. 39, pp. 2137-2142 (1974).
Field George F.
Zally William J.
Hoffman Frank P.
Hoffmann-La Roche Inc.
Leon Bernard S.
Rollins Alton D.
Saxe Jon S.
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