Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1978-12-14
1980-08-05
Daus, Donald G.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
71 95, 2603265FL, 568584, A01N 922, C07D20726
Patent
active
042161525
ABSTRACT:
This invention relates to an improved process for making N-(N'-methylenepyrrolidonyl)-2-substituted anilines which are useful intermediates in the synthesis of agricultural herbicides.
This process of the invention comprises reacting a 2-substituted aniline with N-chloromethylpyrrolidone at about room temperature in the presence of an acid acceptor. Such room temperature alkylation of the aniline prevents excessive side reactions, particularly with a substituent in the 2-position of the aniline, such as an alkenyl group, which is sensitive to alkylating agents which require excessive heating to effective the condensation reaction.
REFERENCES:
patent: 3651085 (1972-03-01), Lunsford
patent: 3769301 (1973-10-01), Olin
Morrison, R. and R. Boyd, "Organic Chemistry", 3rd ed., Allyn and Bacon, Inc., Boston, (1974), p. 742.
Graham David E.
Schneider Louis
Daus Donald G.
GAF Corporation
Jones Lisa
Katz Walter
Kehm Walter C.
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