Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1978-02-22
1979-07-03
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
546255, 546268, 546277, 546332, 2603068D, 260308R, 424269, 424270, C07D21353, C07D28508, A61K 3144, A61K 31425
Patent
active
041600304
ABSTRACT:
The compounds are N-oxy and N-amino guanidines which are histamine H.sub.2 -antagonists. A compound of this invention is N-hydroxy-N'-methyl-N"-[2-((4-methyl-5-imidazolyl)methylthio)ethyl]guanidi ne.
REFERENCES:
Derwent Abstract No. 19437V of Belgian Patent No. 804,144 (Patent Published Feb. 28, 1974-Smith Kline & French).
Derwent Abstract No. 19438V of Belgian Patent No. 804,145-Patent Published Feb. 28, 1974-Smith Kline & French).
Durant Graham J.
Ganellin Charon R.
Owen Geoffrey R.
Edgerton William H.
Foggio Richard D.
Keps Joan S.
Rotman Alan L.
Smith Kline & French Laboratories Limited
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