Process for the reduction of quinidinone to quinidine

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D45304

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active

041744497

ABSTRACT:
Quinidinone is reduced to quinidine through reaction with a reducing agent, selected from aklyl-substituted aluminum hydrides or alkali metal alkyl-substituted aluminum hydrides, in the presence of a stereospecific orienting agent, such as pyridine.

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patent: 4093619 (1978-06-01), Jarreau et al.
Grethe, et al., J. Am. Chem. Soc., vol. 93, No. 22, 5904-5907 (1971).
Woodward, et al., J. Am. Chem. Soc., vol. 67, 1425-1429 (1945).
Doering, et al., J. Am. Chem. Soc., vol. 69, 1700-1710 (1947).

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