Process of making benzodiazepine derivatives

Details Process of making benzodiazepine derivatives Process of making benzodiazepine derivatives

1984-04-24

1986-06-17

Rollins, Alton D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602433, 2602444, 2602457, 564166, 564176, 564185, 564368, C07D24314, C07D40106, C07D40306, C07D41306

Patent

active

045955310

ABSTRACT:
Benzodiazocines corresponding to the formula ##STR1## are converted to benzodiazepines corresponding to the formula ##STR2## of claim 1 by subjecting the benzodiazocine (a) if it is halogen-substituted in the 3-position to a thermal treatment which may also take place in the presence of a nucleophilic agent for the reaction or (b) if the 3-position is hydroxy substituted to treatment with a Lewis acid which is a chlorinating or brominating agent. Whenever the diazepine obtained as the final product has a 2-halogenomethyl group it may then be converted to benzodiazepine which is otherwise substituted in the 2-position.

Affiliated with

Also associated with

Rating

Process of making benzodiazepine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process of making benzodiazepine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process of making benzodiazepine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2272513