Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1975-08-04
1978-01-10
Meyers, Albert T.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
424168, 424172, 424250, 424266, A61K 31455, A61K 3157
Patent
active
040679756
ABSTRACT:
A treatment to alleviate the symptoms of psoriasis consisting of topical application of a cream, ointment or lotion containing as an active ingredient one or more of the following compounds: 6-aminonicotinamide, 6-carbamoylnicotinamide, 6-chloronicotinamide, 6-dimethylaminonicotinamide, 6-formylaminonicotinamide, 6-aminonicotinic acid, 6-aminonicotinic acid methyl ester, 6-hydroxy nicotinic acid, thionicotinamide, 2-aminopyrazinamide and 2-carbamoylpyrazinamide is disclosed. The therapeutic composition may include a single member of the above listed active ingredients present in a total amount of from 0.01 to 5 percent by weight of the total composition, or a plurality thereof present in a preferred concentration range of from 0.01 to 2 percent by weight of the total composition. Topical application of the therapeutic composition in a cream, ointment, or a water or alcohol solution has been found to achieve from substantial to complete remissions of psoriasis in humans.
REFERENCES:
patent: 2199839 (1940-05-01), Renshaw et al.
patent: 2791534 (1957-05-01), Schaaf et al.
patent: 3148115 (1964-09-01), Johnson et al.
patent: 3337570 (1967-08-01), Sherlock et al.
patent: 3415835 (1968-12-01), Stempel et al.
Zackheim, Arch Dermatol, vol. 111, July 1975, pp. 880-882.
Scott Eugene J. Van
Yu Ruey J.
Clarke Vera C.
Meyers Albert T.
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