Enhanced protein production in bacteria by employing a novel rib

Details Enhanced protein production in bacteria by employing a novel rib Enhanced protein production in bacteria by employing a novel rib

1991-01-10

1993-08-03

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 694, 435 712, 4351723, 4352523, 43525233, 43525234, C12P 2100, C12N 1518, C12N 1567, C12N 121

Patent

active

052328406

ABSTRACT:
The present invention provides novel ribosome binding sites useful in enhancing protein production in bacteria. Methods, genes, vectors, bacteria and useful intermediates employing the novel ribosome binding sites of the present invention are also provided. A novel site of interaction different from a Shine-Dalgarno sequence between the 16S ribosomal RNA and messenger RNA is also provided.

REFERENCES:
patent: 952496 (1990-08-01), Studier et al.
patent: 4508827 (1985-04-01), Olsen
patent: 4772555 (1988-09-01), Deboer
patent: 4935370 (1990-06-01), Franke
Tabor et al. (1985), Proc. Natl. Acad. Sci., vol. 82, pp. 1074-1078.
Warburton et al. (1983), Nucleic Acid Res., vol. 11, pp. 5837-5834.
Stanssens et al. (1985), Gene, vol. 36, pp. 211-223.
Deboer et al. (1983), DNA, vol. 2, pp. 231-235.
Seeburg et al. (1983), DNA, vol. 2, pp. 37-45.
Bagdasarian et al. (1981), Gene, vol. 16, pp. 237-247.
Brosius, Jurgen et al. Complete nucleotide sequence of a 16S ribosomal RNA gene from Escherichia coli. Proc. Natl. Acad. Sci. USA 75:4801-4805 (1978).
Dunn, J. J. and Studier, W. F. Complete Nucleotide Sequence of Bacteriophage T7 DNA and the Locations of T7 Genetic Elements. J. Mol. Biol. 166:477-535 (1985).
Gold, Larry et al. Escherichia coli translational initiation factor IF3: A unique case of translational regulation. Proc. Natl. Acad. Sci. USA 81:7061-7065 (1984).
Gren, E. J. Recognition of messenger RNA during translational initiation in Escherichia coli. Biochimie 66:1-29 (1984).
Parker, Michael L. et al. Nucleotide Sequence of Bacteriophage T4 Gene 23 and the Amino Acid Sequence of its Product. J. Mol. Biol. 180:399-416 (1984).
Woese, Carl R. et al. Detailed Analysis of the Higher-Order Structure of 16S-Like Ribosomal ribonucleic Acids. Microbial Rev. 47:621-669 (1983).

Affiliated with

Also associated with

Rating

Enhanced protein production in bacteria by employing a novel rib does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Enhanced protein production in bacteria by employing a novel rib, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Enhanced protein production in bacteria by employing a novel rib will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2269844