Method of encapsulating polyaminopolycarboxylic acid chelating a

Details Method of encapsulating polyaminopolycarboxylic acid chelating a Method of encapsulating polyaminopolycarboxylic acid chelating a

1975-11-10

1977-04-05

Rosen, Sam

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424199, 424365, A61K 31195, A61K 31685, A61K 4700

Patent

active

040162907

ABSTRACT:
A method is provided for transferring a polyaminopolycarboxylic acid chelating agent across a cellular membrane by encapsulating the charged chelating agent within liposomes, which liposomes will be taken up by the cells, thereby transferring the chelating agent across the cellular membrane. The chelating agent is encapsulated within liposomes by drying a lipid mixture to form a thin film and wetting the lipid film with a solution containing the chelating agent. Mixing then results in the formation of a suspension of liposomes encapsulating the chelating agent, which liposomes can then be separated.

REFERENCES:
patent: 3655864 (1972-04-01), Grass et al.

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