Tetralone and indanone compounds

Details Tetralone and indanone compounds Tetralone and indanone compounds

1976-02-18

1977-04-05

Todd, G. Thomas

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

26029358, 26029362, 26029384, C07D21152

Patent

active

040162818

ABSTRACT:
Tetralone and indanone compounds of the formula ##STR1## wherein R.sup.1 is H, OH, alkoxy of 1-4 carbon atoms, cycloalkoxy of 3-6 carbon atoms, F, Cl, Br, NO.sub.2, monoalkylamino or dialkylamino, wherein each alkyl is of 1-4 carbon atoms, alkanoyloxy of 1-6 carbon atoms or alkanoylamino of 1-4 carbon atoms; R.sup.2 is OH or alkoxy of 1-4 carbon atoms or R.sup.1 and R.sup.2 collectively are methylenedioxy; R.sup.3 is H or CH.sub.3 ; Ar is phenyl or phenyl substituted by up to 5 of alkyl of 1-4 carbon atoms, alkoxy of 1-4 carbon atoms, F, Cl, Br or CF.sub.3 ; n is 1 or 2, and physiologically acceptable acid addition salts thereof, are central nervous system depressants.

REFERENCES:
patent: 2820817 (1958-01-01), Sam
patent: 3547923 (1970-12-01), Standridge et al.
patent: 3576811 (1971-04-01), Fusco et al.
patent: 3644372 (1972-02-01), Paragamian
patent: 3850935 (1974-11-01), Nakao et al.
patent: 3974212 (1976-08-01), Cragoe et al.

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