Indolealkylamines and processes for their preparation

Details Indolealkylamines and processes for their preparation Indolealkylamines and processes for their preparation

1979-06-22

1981-02-17

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

546273, 546201, A61K 31445, C07D20908

Patent

active

042515386

ABSTRACT:
Indolealkylamines of the formula ##STR1## wherein Ind is 1-R.sup.4 -2-R.sup.5 -indol-3-yl or the corresponding group in which the benzene ring is monosubstituted to trisubstituted by alkyl, O-alkyl, S-alkyl, OH, F, Cl, Br, CF.sub.3 or CN; A is --(CH.sub.2).sub.4 --, --(CH.sub.2).sub.3 --CO-- or --CO--(CH.sub.2).sub.2 --CO--; R.sup.1 is H or methyl; R.sup.2 is H or together with R.sup.3 is a C--C bond; R.sup.3 is H or together with R.sup.2 is a C--C bond; R.sup.4 and R.sup.5 are each H, alkyl, or phenyl; and Ar is phenyl or phenyl monosubstituted or disubstituted by alkyl, F, Cl, Br, I or CF.sub.3 ; wherein alkyl in each case is of 1-4 carbon atoms;

REFERENCES:
patent: 3217011 (1965-11-01), Zenitz
patent: 3238215 (1966-03-01), Zenitz
patent: 3494920 (1970-02-01), Herbst
patent: 3639414 (1972-02-01), Archer
patent: 3821234 (1974-06-01), Koppe et al.
patent: 4021431 (1977-05-01), Zenitz

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