Process for preparing 5-substituted-3-furaldehydes

Details Process for preparing 5-substituted-3-furaldehydes Process for preparing 5-substituted-3-furaldehydes

1988-10-18

1990-06-19

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549209, 549318, 549320, 549321, 549322, 549323, 549324, 549473, 549479, 549480, 549484, C07D30734

Patent

active

049355309

ABSTRACT:
A process for preparing 5-substituted-3-furaldehydes which comprises reacting 3-furaldehyde with lithium morpholide, followed by sec-butyl lithium, followed by an electrophile.

REFERENCES:
patent: 4195026 (1980-03-01), Kraus
patent: 4221585 (1980-09-01), Levitt
patent: 4500520 (1985-02-01), Haber
Tetrahedron Letters, vol. 24 (52), pp. 5835-5838, 1983.
Tetrahedron Letters, vol. 26 (47), pp. 5827-5830, 1985.
Tetrahedron Letters, vol. 27 (38), pp. 4533-4536, 1986.

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