Composition for the oral administration of pharmaceuticals

Details Composition for the oral administration of pharmaceuticals Composition for the oral administration of pharmaceuticals

1988-05-06

1990-06-19

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424497, 424498, A61K 916

Patent

active

049352474

ABSTRACT:
The invention relates to a new composition for use on a pharmaceutical granule. The composition is three-layered, comprising as the innermost layer a substantially pure fat, as the middle layer a mixture of fat and polymer, and as the outermost layer again a substantially pure fat.
The composition according to the invention produces a preparation which is tasteless, especially when administered in the form of a powder or a mixture, even if the phrmaceutical to be dosed has a bad taste. Also, the preparation keeps well in mixture, and it enables a pharmaceutical to be transported past the stomach for release/absorption at the beginning of the small intestine.

REFERENCES:
patent: 2828206 (1958-03-01), Rosenberg
patent: 2921883 (1960-01-01), Reese et al.
patent: 2963402 (1960-12-01), Nalin et al.
patent: 3080294 (1963-03-01), Shepard
patent: 3119742 (1964-01-01), Heimlich et al.
patent: 3256153 (1966-06-01), Heimlich
patent: 3432593 (1969-03-01), Shepard
patent: 4460563 (1984-07-01), Calanchi
patent: 4650665 (1987-03-01), Kronenthal et al.

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