Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1996-11-08
2000-10-10
Priebe, Scott D.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4353201, 435325, 4352523, 43525411, 536 231, 536 235, C07H 2100, C12N 115, C12N 121, C12N 510, C12N 1512, C12N 1563
Patent
active
061300616
ABSTRACT:
A human stem cell antigen 2 polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for stimulating thymocyte maturation and differentiation, protecting neuronal cells, preventing rejection during organ transplantation, treating PNH, Alzheimer's Disease and inflammation is disclosed. Diagnostic assays for identifying mutations in nucleic acid sequence encoding a polypeptide of the present invention and for detecting altered levels of the polypeptide of the present invention for detecting diseases, for example, cancer, are also disclosed.
REFERENCES:
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Genbank Accession No. R50636 (Oct. 15, 1995).
Yamakawa et al. (1995) Human Molecular Genetics 4(4):709-716.
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Classon et al. (1995) 9th International Congress of Immunology, p. 727, Abstr. No. 4312.
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Gentz Reiner
Gocayne Jeannine D.
Ni Jian
Yu Guo-Liang
Human Genome Sciences Inc.
Priebe Scott D.
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