Useful hemi-hydrate form of a cerebral function enhancing agent

Details Useful hemi-hydrate form of a cerebral function enhancing agent Useful hemi-hydrate form of a cerebral function enhancing agent

1993-10-04

1995-03-28

Ford, John M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544329, C07D40114, A61K 31505

Patent

active

054017440

ABSTRACT:
The hemi-hydrate form of the cerebral function enhancing agent 1-[[1-[2-(trifluoromethyl)-4-pyrimidinyl]-4-piperidinyl]-methyl-2-pyrrolid inone, or BMY-21502 as it is more commonly designated, is an improved form of drug substance having equivalent biopharmaceutical properties compared to the known anhydrous form but providing cost, safety and ecological advantages in manufacture over the known anhydrous form.

REFERENCES:
patent: 4826843 (1989-05-01), Mattson et al.
patent: 4963678 (1990-10-01), Madding et al.
patent: 5098904 (1992-03-01), Mattson et al.

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